| abstract |
The present invention relates to compounds useful as TRPM8 activity modulators, such as compounds of formula (I) and subgenera and species thereof; personal products containing these compounds; and uses of these compounds and personal products, in particular Includes the use of augmentation or induction of chemeristic stimuli such as cool or cool. In another embodiment, the present invention provides a method of modulating the activity of transient receptor potential channel melastatin member 8 (TRPM8) comprising contacting the receptor with a compound or salt or solvate thereof. |