| abstract |
The present invention relates to novel piperazine derivatives and their use as active ingredients in the manufacture of pharmaceutical compositions. The present invention also relates to pharmaceutical compositions comprising one or more of these compounds and related aspects including their use as medicaments for the treatment or prevention of protozoal infections, particularly malaria. Wherein X represents — (CH 2 ) 0-2 — or — (C═O) —; n represents an integer 0, 1 or 2; R 1 —R 4 represents claim 1 As you did. |