| abstract |
Isoxazole-5-one derivatives (I) are new. Isoxazole-5-one derivatives of formula (I) and their tautomers are new. A = optionally substituted heterocyclyl; Q = R1 or E1-R1; R = R2 or E2-R2; E1-R1 = CO-R1, COO-R1, CON(R3)(R1), CO-CO-R1, CO-CO-OR1, CO-CO-N(R3)(R1) or C(=S)-N(R3)(R1); E2-R2 = CO-R2, COO-R2, CON(R4)(R2), CO-CO-R2, CO-CO-OR2, CO-CO-N(R4)(R2) or C(=S)-N(R4)(R2); R1-R4 = H or optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heteroaryl. |