abstract |
Cell surface receptor binding drug delivery conjugates, methods of using the conjugates, and pharmaceutical compositions comprising the conjugates for use in the treatment of pathologies caused by pathogenic cell populations are provided. A drug delivery conjugate of the following formula, or a pharmaceutically acceptable salt thereof and a composition containing them: BLD [B is a binding or targeting ligand; L is a releasable linker; D is tubulin or a conjugate of tubulin as exemplified below] [Selection] Figure 7 |