| abstract |
PROBLEM TO BE SOLVED: To suppress an increase in impurities associated with formulation of benzimidazole-7-carboxylic acid or its derivative represented by candesartan or candesartan cilexetil, and prevent a decrease in daily content As well as methods for preparing the compositions. It has been found that when a polyhydric alcohol is added to benzimidazole-7-carboxylic acid or a derivative thereof, a stable preparation can be obtained. In other words, the establishment of a technical idea that the addition of polyhydric alcohols can significantly suppress the decomposition of active ingredients, suppress the increase in impurities accompanying formulation, and prevent the daily content of active ingredients from decreasing. did. [Selection figure] None |