abstract |
Where R 1 is H, methyl or ethyl; R 2 is H, OH, fluorine, C 1 -C 4 linear or branched alkyl, C 1 -C 6 alkoxy, wherein in alkoxy, the alkyl group is linear or branched, or C 3- It is a C 5 cycloalkyl moiety; R 3 is H, methoxy, methyl or ethyl; Or R 2 and R 3 together form a bridge —O—CH 2 —O— between the phenyl carbon atoms to which they are attached; R 4 is OH or methoxy; R 5 and R 6 are independently H or methyl; R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are (I) when R 2 and R 3 together form a bridge —O—CH 2 —O— with the phenyl carbon atom to which they are attached, R 1 , R 5 , R 6 are H And R 4 is OH; and (ii) when R 4 is OH and R 1 -R 3 is H, then at least one of R 5 or R 6 is methyl, (Including salts thereof). |