| abstract |
The present invention relates to a cholesteryl ester transfer protein (CETP) inhibitor / formula of formula (Ia) and (Ib) wherein A, B, C, R 1 and R 14 are described herein Pharmaceutical compositions comprising such inhibitors, as well as certain plasma lipid levels, including high density lipoprotein (HDL) -cholesterol, and certain low density lipoprotein (LDL) -cholesterol and triglycerides Such inhibitors are used to reduce the levels of other plasma lipids, thereby causing atherosclerosis in certain mammals, including humans (ie those having CETP in their plasma) And low levels of HDL cholesterol and / or high levels of LDL-cholesterol and triglycerides, such as cardiovascular disease It provides for the treatment of diseases affected by. |