abstract |
(57) [Object] To provide a novel compound having MIP-1α / RANTES receptor antagonistic activity. SOLUTION: Formula (1) Wherein X 3 and Y 3 are the same or different, A phenyl group or a pyridyl group which may be substituted with a halogen atom, Represents a single bond or a double bond, Q is - (CH 2) n- (N represents an integer of 1 to 3) or - (CH 2) m -CH = (m represents an integer of 0 to 2), and R 5 Represents a hydrogen atom or a C 1-6 alkoxy-carbonyl group. Or a salt thereof. [Effect] The above preparation is excellent in MIP-1α / RANTE It has S receptor antagonism. |