abstract |
Compounds having affinity for ORL1 (opioid receptor-like) receptor, compounds currently available, for example, compounds having agonist activity of μ, δ, and κ receptors greater than morphine, and opioids Provide a method for reducing side effects of analgesics. Specific examples include the compounds shown below. 1- [1-Dibenzocycloheptyl-4-piperidinyl] -3- [1-oxo-ethyl] -1,3-dihydro-2H-1,3-benzamidazol-2-one |