| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_139aff3556869a0208383f5dac575e98 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
| filingDate |
2012-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d80daa7f1d1a5cbd0e2c0e1c96951d2 |
| publicationDate |
2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2468745-A1 |
| titleOfInvention |
Process for the preparation of lapatinib and the salts thereof |
| abstract |
The present invention refers to a new process for the synthesis of the pharmaceutical active ingredient Lapatinib and the salts thereof. n In particular, the present synthesis is performed using intermediates in which the hydroxyl function is protected by the tetrahydropyranyl group hence entailing greater solubility of the intermediates in the common organic solvents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016096826-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9169236-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9359333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9024023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2754662-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014170910-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-VI20130003-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2921490-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014188226-A2 |
| priorityDate |
2011-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |