| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_139aff3556869a0208383f5dac575e98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c8edcfd0e0cc7390d445a81a1207d9d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
| filingDate |
2015-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ac8cc6c852400da1cd529e322210b68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d8aad46597b8fd3c269430c87281ac |
| publicationDate |
2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9169236-B2 |
| titleOfInvention |
Efficient process for the preparation of lapatinib and salts thereof by means of new intermediates |
| abstract |
The present invention refers to a new efficient process for the synthesis of the active pharmaceutical ingredient Lapatinib and salts thereof. In particular, the present synthesis is carried out employing new intermediates in which the amine function is protected by a group cleavable in basic milieu that provides a higher overall yield of the synthesis process. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9359333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261199-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11230558-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10865214-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008341-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10487091-B2 |
| priorityDate |
2013-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |