abstract |
A benzene, pyridine or pyrimidine derivative having the below shown formula is novle and useful as an anti-arteriosclerotic agent.n wherein R 1 stands for a lower alkyl group, an amino group which may be substituted, or the like; R 2 stands for a group represented by the formula:n (wherein R 16 stands for an alkyl group having 1 to 6 carbon atoms, or the like) or the like; R 3 stands for a group represented by the formula: -O-(CH 2 ) m -Y (Y stands for an imidazolyl or piperazinyl group, or the like and m is 1 to 6) or the like; R 5 stands for a hydrogen atom, a lower alkyl group, or the like; A stands for a group represented by the formula:n (wherein R 6 stands for a hydrogen atom, a lower alkyl group, or the like), -N =, or the like; and B stands for a group represented by the formula:n (wherein R 4 stands for a hydrogen or the like), -N=, or the like. |