abstract |
A novel benzene derivative useful as a prophylactic and a remedy for arteriosclerosis, and a cholesterol O-acyltransferase inhibitor containing the same as the active ingredient. The derivative is represented by general formula (I), wherein R¹ represents optionally protected carboxyl or a group represented by general formula (a) (wherein R⁵ represents lower alkyl or hydroxyalkyl, and R⁶ represents hydrogen or hydroxy); R² represents hydrogen, lower alkyl, etc.; R³ and R⁴ represent each hydrogen or hydroxy; and p represents an integer of 1 to 6. |