abstract |
There are new 14α, 17α-ethano-estratrienes of the general formula I wherein R¹ is a hydrogen atom, an alkyl or acyl group having 1 to 12 carbon atoms, R² is a hydrogen atom or a methyl group, R³ is a hydrogen atom or an acyl group having 1 to 12 carbon atoms and where R⁴ is an α- or ß-standing alkyl radical with 1 to 8 carbon atoms or an α, β-alkenyl or an α, β-alkynyl radical, both with 2 to 8 carbon atoms, optionally having several double bonds, mean, described and a process for their preparation. The new compounds have strong estrogenic activity. |