| abstract |
Compounds of Formula I are novel and useful as cardiovascular agents, particularly anti-arrhythmic agents:or the 5-amino tautomerthereof or a salt of either, wherein R<sup>1</sup> is C1-10alkyl, C<sub>2</sub>-<sub>l</sub>oalkenyl, C<sub>2</sub>-<sub>l</sub>oalkynyl or C<sub>3</sub>-iocycloalkyl, any of which is optionally substituted, and R<sup>2</sup> to R<sup>6</sup> are independently selected from hydrogen, halogen atom, C1-6alkyl, alkenyl or alkynyl (all optionally substituted by one or more of halogen, hydroxy and aryl), amino, mono- or di-substituted amino, alkoxy (optionally substituted by one or more of halogen, hydroxy and aryl), alkenyloxy, acyl, acyloxy, cyano, nitro, aryl and alkylthio groups or any adjacent two of R<sup>2 </sup>to R<sup>6</sup> are linked to form a (-CH=CH-CH=CH-) group. |