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bibliographicCitation Wang A, Li X, Chen C, Wu H, Qi Z, Hu C, Yu K, Wu J, Liu J, Liu X, Hu Z, Wang W, Wang W, Wang W, Wang L, Wang B, Liu Q, Li L, Ge J, Ren T, Zhang S, Xia R, Liu J, Liu Q. Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML. J. Med. Chem. 2017 Oct 17;60(20):8407–24. doi: 10.1021/acs.jmedchem.7b00840.
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title Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476245_PMID28956923_VALUE1
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476282_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381859339_AID1476271_PMID28956923_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381884488_AID1476271_PMID28956923_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381886613_AID1476271_PMID28956923_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476212_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476289_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476206_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476242_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476273_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476265_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381851312_AID1476270_PMID28956923_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476211_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476268_PMID28956923_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136940589_AID1476271_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476295_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476244_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476224_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476255_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381884488_AID1476270_PMID28956923_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476209_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476309_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476232_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476297_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476284_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476275_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476317_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476288_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476271_PMID28956923_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866848_AID1476271_PMID28956923_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381860206_AID1476268_PMID28956923_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381868299_AID1476270_PMID28956923_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476325_PMID28956923_VALUE1
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476214_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476334_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476341_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381850205_AID1476268_PMID28956923_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476254_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476247_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381851312_AID1476271_PMID28956923_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381847511_AID1476270_PMID28956923_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476230_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476292_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476218_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866848_AID1476268_PMID28956923_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476247_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476332_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381868865_AID1476269_PMID28956923_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476286_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476270_PMID28956923_VALUE25
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476268_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476337_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476208_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381860146_AID1476269_PMID28956923_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476264_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476210_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381841725_AID1476268_PMID28956923_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476307_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476306_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476311_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476256_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136940589_AID1476268_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476333_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476269_PMID28956923_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476277_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381847511_AID1476268_PMID28956923_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476202_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476250_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476246_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476299_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381883165_AID1476269_PMID28956923_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476295_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381850205_AID1476269_PMID28956923_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476287_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476318_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476316_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381850205_AID1476271_PMID28956923_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476338_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476222_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476204_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381860146_AID1476268_PMID28956923_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476296_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476261_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871159_AID1476268_PMID28956923_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381839237_AID1476268_PMID28956923_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476312_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871537_AID1476269_PMID28956923_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885130_AID1476270_PMID28956923_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381868299_AID1476269_PMID28956923_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476326_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381841725_AID1476271_PMID28956923_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476310_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381855905_AID1476270_PMID28956923_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381839237_AID1476271_PMID28956923_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476298_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476292_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871159_AID1476270_PMID28956923_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476288_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381851312_AID1476269_PMID28956923_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476253_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871159_AID1476269_PMID28956923_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476320_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476291_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871537_AID1476268_PMID28956923_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381881655_AID1476268_PMID28956923_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381860206_AID1476270_PMID28956923_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476202_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476273_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476203_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476256_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476335_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849905_AID1476270_PMID28956923_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381846146_AID1476269_PMID28956923_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381860206_AID1476271_PMID28956923_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476213_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476248_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476276_PMID28956923_VALUE1
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476291_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476267_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476241_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476252_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381855905_AID1476271_PMID28956923_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476285_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381840318_AID1476268_PMID28956923_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381860146_AID1476271_PMID28956923_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381839237_AID1476269_PMID28956923_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476253_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381847511_AID1476269_PMID28956923_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476319_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476279_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476274_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381868865_AID1476270_PMID28956923_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476272_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476283_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476280_PMID28956923_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476290_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103699058_AID1476243_PMID28956923_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381886613_AID1476269_PMID28956923_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381843989_AID1476268_PMID28956923_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885613_AID1476234_PMID28956923_VALUE1
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8999
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1436
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID780
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID902
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11113
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2324
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2322
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2321
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2872
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID695
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID984
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3815
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5979
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4331
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1022
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5156
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4921
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID892
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5159
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6793
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1024
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3932

Total number of triples: 396.