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filingDate 1999-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3adb130ccf3c976ed2946aa3c29b3a69
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publicationDate 1999-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9961032-A1
titleOfInvention Process for producing composite preparation containing nucleic acid
abstract A process for producing a homogeneous nucleic-acid-containing composite preparation of good quality which is capable of sterilization by filtration and is characterized by containing no coarse particles having a size of 7 νm or larger, which are regarded as unsafe for the human body. The process for producing the preparation, containing a composite of a cationic carrier with a nucleic acid polymer, is characterized in that two single-stranded nucleic acid polymers capable of at least partly forming a double-stranded state are separately added, each in the single-stranded state, to either a cationic carrier or a material from which the cationic carrier is to be formed, and all these ingredients are subjected to a dispersing treatment.
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