abstract |
Methods of detecting synucleins to identify and diagnose synucleinopathies are provided. In addition, methods of treating such neurodegenerative disorders via modulation of production of selected synucleins and/or the formation of filamentous intracytoplasmic neuronal and glial inclusions from selected synucleins are described. A monoclonal antibody raised against Lewy bodies and specific for human α-synuclein is also provided. |