http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014533357-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-387 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2012-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014533357-A |
| titleOfInvention | Use of anti-α-synuclein antibodies to diagnose high levels of α-synuclein in the brain |
| abstract | The present invention relates to the use of anti-α-synuclein antibodies to diagnose high levels of α-synuclein in the brain. Specifically, the present invention relates to an anti-α-synuclein antibody or antigen thereof capable of binding to α-synuclein with sufficient activity to alter the net outflow of α-synuclein from brain to blood or from brain to CSF. It relates to a method for assessing the level of α-synuclein in plasma or CSF after administration of a binding fragment to a subject. The method of the present invention, for example, analyzes the level of α-synuclein in a plasma sample obtained from a subject at predetermined intervals after peripheral administration of an anti-α-synuclein antibody or antigen-binding fragment thereof to the subject. Analyzing that the antibody or fragment thereof can bind to the alpha-synuclein with sufficient affinity to alter the net outflow of the alpha-synuclein from the brain to the blood. Including. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-6273338-B1 |
| priorityDate | 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.