| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ecdb312613927aa46246fe01fb23136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a05b9b88a36b761667cd81e89c9cf1a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58cb5a5b27b27654757026260acf5938 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-04 |
| filingDate |
1998-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe6978ed487e97ef5edd5aaf57c6cb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9d755b58c5ddeac271b3e4eb0b7c4a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3085b60820be924601585727cc99d925 |
| publicationDate |
1999-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9931101-A1 |
| titleOfInvention |
Adenosine receptor antagonists with improved bioactivity |
| abstract |
Xanthine A1AR antagonist having halogenated N-1 and/or N-3 side chains are provided. The methods for the syntheses of such antagonists are also provided. The methods for using such antagonist labeled with carbon-11, fluorine-18 or isotopes of iodine such as iodine-123 for medical diagnostic imaging of the A1AR in patients are provided. Methods for improving the potency and duration of action of xanthine A1AR antagonist by halogenation of N-1 and N-3 propyl substituents is provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013510138-A |
| priorityDate |
1997-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |