| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cb8ba5cb6708607fc884a48b670e551
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bb01ba853ca5cd035031fbd749a10cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f47246a0feb4cfaa066723a31c6133d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d30aa46afa14ded1bb472fd6664f4e92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_765ba5b8b178b5b1ef4d5205c99b7e63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf4d7ea74305417887eba1611ae878b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
1998-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35861d85fb4891fdb4f63fc84614de05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4de6b227a6c267bcec3a3c07fa4d7bee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fb8076168c4d225d3747764c0a8f584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f2ce59a9c73c94a187195b0ddd99e1a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f029a00ee4b718a1331bbe92af5b642 |
| publicationDate |
1998-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9850078-A1 |
| titleOfInvention |
Lipophilic and/or lytic peptides for specific delivery of nucleic acids to cells |
| abstract |
The invention relates in part to molecular complexes for delivering macromolecules (e.g., nucleic acid molecules) into cells. These molecular complexes can comprise lipophilic peptides that condense and stabilize the macromolecule. These lipophilic binding peptides can also comprise moieties that target the macromolecule to specific cells in an organism. In addition, the molecular complexes can comprise lipophilic peptides that can lyse endosomal structures within cells and thereby enhance delivery of the macromolecule into cells. The invention also relates in part to methods of delivering macromolecules to cells using the molecular complexes described herein. Thus, the present invention provides for efficient and specific delivery of nucleic acid molecules into cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0202790-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013252901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005085458-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1052287-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1052288-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1052287-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113149869-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9334303-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019182867-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10933139-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1170373-A1 |
| priorityDate |
1997-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |