| abstract |
This invention relates to compositions and methods for delivering a polynucleotide to ocularncells, in vitro, ex vivo or in vivo. More particularly, the invention resides, inter alia, in thenuse of a cationic peptide and a fusogenic peptide (or a combination thereof) in thenpreparation of a composition for delivering a polynucleotide to an ocular cell in vitro, exnvivo or in vivo. The invention can be used in many different areas such as experimentalnbiology, preclinical and clinical research, as well as in therapeutic or prophylactic treatmentsnof mammalians, in particular human subjects. |