| abstract |
An adamantane derivative having a functional group such as nitro, amino, hydroxyl, carboxyl, hydroxymethyl or isocyanato is oxidized with oxygen in the presence of an imide compound of general formula (2) (such as N-hydroxyphthalimide) or both of this imide compound and a cocatalyst (such as a transition metal compound). This process can efficiently provide an adamantane derivative having a hydroxyl group in addition to the functional group such as nitro, amino, hydroxyl, carboxyl, hydroxymethyl or isocyanato; wherein R?1 and R2¿ each represent hydrogen, halogen, alkyl, aryl or cycloalkyl, or R?1 and R2¿ may be bonded together to form a double bond, or an aromatic or non-aromatic ring; Y represents O or OH; and n represents 1 to 3. |