http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9838337-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efaece3f57d915a44fb0784b21caeab8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 1998-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9599ac43b874871bf69957eb3e714398 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_747ac117d98070272f27402723c84ea0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c64001e0fdbe7e37937b2d20c8b6ca4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14f90b20d40b8d65036b039aa6bc5370 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c0a74137206e84c1a26fd75f65cca33 |
publicationDate | 1998-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9838337-A1 |
titleOfInvention | Methods for cleaving dna with nucleotide integrases |
abstract | The present invention provides methods, using a nucleotide integrase, for cleaving nucleic acids substrates at specific sites and inserting a nucleic acid molecule into the cleaved substrate. The method of cleaving one strand of a double-stranded DNA substrate comprises providing a nucleotide integrase comprising a group II-intron RNA having two hybridizing sequences capable of hybridizing with two intron RNA binding sequences on the one strand of the substrate and a group II-intron encoded protein which binds to a first sequence element of the substrate. The method of cleaving both strands of a double-stranded DNA substrate comprises providing a nucleotide integrase comprising a group II-intron RNA having two hybridizing sequences capable of hybridizing with two intron RNA binding sequences on one strand of the substrate and a group II-intron encoded protein capable of binding to first and second sequence elements in the recognition site of the substrate. The method of cleaving a single-stranded nucleic acid substrate comprises providing an integrase having two hybridizing sequences capable of hybridizing with two intron RNA-binding sequences of the substrate and a group II-intron encoded protein. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8090003-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544422-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7592161-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE44530-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE45237-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE44591-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6358712-B1 |
priorityDate | 1997-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.