abstract |
A thiazole compound of formula (I), wherein T is lower alkylene; u is 0 or 1; R?1 and R2¿ are the same or different and are each H, or lower alkyl, etc.; R3 is (1) or (2); R4 is H or lower alkanoyloxy-lower alkyl, which shows inhibitory activity or protein kinase C(PKC, Ca2+/phospholipid-depending serine/threonine protein phosphatase), and are useful as a protein kinase C inhibitor. |