| abstract |
The invention concerns a compound of formula (I) wherein: -A-B- is of the formula ⊃C=CH- or ⊃CHCH2-; R?1 and R2¿ are independently hydrogen or fluorine; R?3 and R4¿ are independently hydrogen or methyl; D is O, S, SO, SO¿2? or of the formula R?5¿N wherein R5 is hydrogen or benzyl; or R5 is of the formula R6CO-, or R6SO2- wherein R6 is, for example, amino, or R6 is of the formula R7C(O)O(1-6C)alkyl wherein R7 is, for example, optionally substituted phenyl or optionally substituted (1-6C)alkyl, or R6 is of the formula R8O-, wherein R8 is benzyl or optionally substituted (1-6C)alkyl; or R5 is of the formula R?10CH(R9)(CH¿2)m- wherein m is 0 or 1, R9 is, for example, fluoro and R10 is hydrogen or (1-4C)alkyl; and pharmaceutically-acceptable salts thereof; processes for their preparation; pharmaceutical compositions containing them and their use as antibacterial agents. |