abstract |
A compound of formula (I):whereinR1 is hydroxy or of the formula -NHC(=O)(1-4C)alkyl or -NHS(O)n(1-4C)alkyl wherein n is 0, 1 or 2;R2 and R3 are independently hydrogen or fluoro;R4 and R5 are independently hydrogen or methyl;>A-B- is of the formula >C=CH-, or >C(OH)CH2-;>X-Y- is of the formula >C=CH-, or >CHCH2-; andD is S, SO, or SO2;or a pharmaceutically-acceptable salt thereof. |