| abstract |
A compound of formula (I), wherein R1 is heterocyclic group, X is (CH¿2?)a in which a is 0 or 1, O or S, Y is CH2, O, S or N-R?2¿ in which R2 is hydrogen or lower alkyl, Z is O or H¿2?, and m and n are each 0 or 1, and pharmaceutically acceptable salts thereof, which is useful as a medicament for prophylactic and therapeutic treatment of NOS-mediated diseases. |