abstract |
The invention relates to heterocyclic carbamates of formula (I) in which X denotes a nitrogen atom or the group CR4 and Y denotes a nitrogen atom or the group CR5, where R?2 and R3¿ independently of one another stand for radicals of the following meaning: hydrogen atoms, C¿1?- to C6- lower alkyl radicals, C1- to C6- lower alkoxy radicals, C1- to C6- lower alkylthio radicals, halogen atoms, nitro groups, hydroxyl groups, trifluoromethyl radicals, cyano radicals, sulpho radicals, C1- to C6- lower alkylsulphonyl groups, carboxylic acid groups, C1- to C6- lower alkoxycarbonyl radicals, C1- to C6- lower alkoxycarbonyloxy radicals, acetamido radicals, benzamido radicals or the group -N(R6)R7, m and n independently of one another stand for a hydrogen atom or a C1- to C6 lower alkyl radical, and in which R?1, R4 and R5¿ have the meanings given in the description; their use as antithrombotics and as inhibitors of enzymes breaking down connective tissue, in particular granulocyte elastase. |