| abstract |
A tetrazole derivative of general formula (1), where A represents -CH=CH-, -CH2-CH2-, -CH2O-, an oxygen atom or a sulfur atom or, in the case where A does not interconnect the adjacent aromatic rings, it represents two hydrogen atoms each bonded to the adjacent aromatic ring; V represents -CH=CH- or a sulfur atom; X and Y each independently represents an alkoxy group, a halogen atom or a hydrogen atom; (a) W represents a bond, Z represents a carbon atom or methine, and B either forms a bond together with Z or represents a hydroxyl group, or (b) W, Z and B represent a bond, a nitrogen atom and a hydrogen atom, respectively, or (c) W, Z and B represent an oxygen atom, methine and a hydrogen atom, respectively; p represents an integer of 2 or 3; and n represents an integer of 1-6 or a pharmacologically acceptable salt thereof, or an antihistamine, an anti-allergic agent or an asthma treating agent containing the same. |