| abstract |
The invention relates to 2-pyridone derivatives of general formula (I) in which Ar1 is an optionally substituted phenyl ring; Ar2 is an optinally substituted phenyl ring; R1 is hydrogen or C¿1-4?alkyl; R?2¿ is hydrogen or C¿1-4?alkyl; R?3¿ is hydrogen or C¿1-4?alkyl; R?4 and R5¿ are the same or different and are each hydrogen, C¿1-4?alkyl or C1-4alkylAr?1, or R4 and R5¿ together form a group (CH=CH)¿2?; and X is CH2 or NR?6¿ in which R6 is hydrogen or C¿1-4?alkyl or a salt thereof, and their use in therapy as gastric acid secretion inhibitors. |