| abstract |
Heterocyclic compound of the formula: R1-A-CO-X-Y-R2, in which R1 is carboxy(lower)alkyl or protected carboxy(lower)alkyl, R2 is optionally substituted aralkyl, X is optionally substituted arylene, Y is -O- or (a), wherein R6 is hydrogen, lower alkyl, optionally substituted aralkyl or amino-protective group, and A is a bivalent radical derived from imidazopyridine, azulene, thiophene, pyrrolo[2,3-b]pyridine, quinolone, indazole or dihydrobenzimidazole, each of which may be substituted by one or more suitable substituent(s), which are useful as a testosterone 5α-reductase inhibitor. |