| abstract |
Compounds of formula (I), wherein A is a C1-C8 alkyl, perfluoroalkyl, cycloalkyl, aryl, substituted aryl, heterocyclic or substituted heterocyclic group; B is defined to include a variety of linking groups including straight and branched-chain alkylene and alkenylene groups as well as groups containing an ether, thio-ether, amine or amide group and various substituted and cyclic variations thereof; and R?1, R2 and R3¿ are each H or CH¿3?; are PAF antagonists of value in the treatment of allergic and inflammatory conditions in humans. |