| abstract |
Novel materials and methods for guided tissue generation are disclosed. The compositions of the invention comprise a biodegradable membrane comprising a first and a second side, wherein said first side of said membrane comprises one or more biologically active substances, not present on or in said second side. Alternatively, both sides of the membrane may comprise one or more biologically active substances. One or both sides of said membrane may be at least partially coated with a second resorbable membrane layer of varying thickness and/or composition, thereby allowing controlled release of said biologically active substance(s). The compositions, materials and methods of the invention have therapeutic utility for guiding tissue regeneration in animals, including humans. |