| abstract |
Medical devices, most particularly prosthesis, are defined having at least one porous tissue-mating surface. The tissue-mating surface of the device includes therein a biodegradable carrier, such as a biodegradable polymer. The pores or intersticial spaces of the tissue-mating surface of the device are impregnated with the biodegradable polymer. The prosthesis of the present invention provides for enhanced rigid fixation, as pores at the surface of said device provide for bony ingrowth as the biodegradable carrier, i.e., polymer, degrades. Methods for preparing said prosthesis are described. Methods for delivering a pharmacologically active substance by including a pharmacologically active substance in the biodegradable carrier (e.g., polymer) are also disclosed. |