| abstract |
The drug is in the form of granules each consisting of a neutral core (sucrose + starch) covered with a first layer of fenofibrate mixed with an excipient, and a second microporous outer layer of an edible polymer. The administration of a 250 mg capsule per day instead of three doses of 100 mg thus makes it possible to reduce the dosage and the number of administrations thanks to the gradual and delayed release of fenofibrate. Maintain a minimum dose in the blood, avoid temporary high concentrations, and reduce the total amount ingested. |