| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98f8badbfa322f259f69962564ca700c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26 |
| filingDate |
2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0945fc310d6e3d7181e470a4453a40e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e78690f76abb41f7faf3a20b303a4fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ab76794fc8b794197cbb70d29f78b19 |
| publicationDate |
2003-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6531158-B1 |
| titleOfInvention |
Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
| abstract |
The present invention provides a drug delivery system for the oral administration of a hydrophobic active ingredient. The active ingredient's post-ingestion dissolution rate and its corresponding bioavailability can be optimized by intimately mixing a micronized hydrophobic drug with suitably sized inert particles to a dispersion that will facilitate desired bioavailability. In a particular embodiment, the hydrophobic active ingredient is fenofibrate. Suitably sized inert particles include microcrystalline cellulose and lactose. Dispersion may be monitored by microscopic visualization. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018187849-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014091318-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9566258-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9314447-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008220076-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010086586-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012027852-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9161911-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9603803-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009197903-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010166857-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011305733-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9937142-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009042114-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011129579-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010159010-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2018251624-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008050450-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010040689-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008020046-A1 |
| priorityDate |
2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |