abstract |
A gel based on fibrine and antibiotic for the treatment of an infected bone contains fibrinogene, a solution containing thrombin and enriched with calcium ions as well as an antibiotic of the tobramycin, gentiamycin group and/or one of their physiologically acceptable salts. The gel may be prepared by mixing the fibrinogene in the form of a lyophilisate or cryoprecipitate with an antibiotic in sterile conditions and then adding a thrombin solution enriched with calcium ions. |