abstract |
The present invention relates to a method for screening for a compound that binds to human IL-33 protein and inhibits IL-33, a composition for inhibiting IL-33 protein, comprising a compound selected through screening, and a pharmaceutical composition for treating an allergic disease comprising same. A compound fragment that binds to IL-33, selected by using a method for screening for compound fragments that bind to IL-33 protein, according to the present invention, binds to the IL-33 protein more specifically and strongly to inhibit the IL-33 protein, and thus can be effective in treating or preventing allergic diseases, such as asthma and atopic dermatitis. |