| abstract |
Methods for diagnosing active tuberculosis and progression to active tuberculosis are disclosed. In some embodiments, the method may comprise (a) obtaining a sample of RNA from a subject, e.g., a subject having latent tuberculosis and/or symptoms of active tuberculosis; and (b) measuring the amount of RNA transcripts encoded by PLAAT4, CYB561, GBP5, SMAD7, LAX1, CDKN1C, CA5B, EPHA4 and CD83 in the sample, to produce gene expression data. This data can be used for the diagnosis and to make treatment decisions. |