http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022148822-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59a31fa4c10a87752fbeae85ebfeae0a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-19012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-50 |
| filingDate | 2022-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5347af00d7134c85fe932e187ec9b524 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16025807a53bc169bbada0d50f8b433f |
| publicationDate | 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022148822-A1 |
| titleOfInvention | Usp5 binding survival-targeting chimeric (surtac) molecules & uses thereof |
| abstract | Chimeric molecules that include a USP5 binding domain and uses thereof for deubiquitinating a ubiquitinylated protein, and or for treating a disease in a subject in need are provided herein. Further, Survival-Targeting Chimeric (SURTAC) molecules that include a USP5 binding domain linked to a target protein binding domain are disclosed herein, as are their uses for deubiquitination and treating disease. In some instances, the target protein is a ubiquitinylated protein, wherein a bound USP5 enzyme may proteolytically remove ubiquitin from the target ubiquitinylated protein. |
| priorityDate | 2021-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1001.