| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y406-01001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-00 |
| filingDate |
2020-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2a64adfd89e2104778932db0bf6ac7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7a1e89e9490a8c5a3f60432c6d4ed1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0a53adbc70c5669aad1540117ffa863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_789892f232bf219b5c1a7e5229ccbc9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_506f8afe222d104c7ab425838febfde4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c48c73390b5d9daf1d859c0f6ec5aec5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68ebec6364859367898322035e5022e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c97379786288b6437f4020ffd2641e51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b68caf3260815a443eac98b41da4ca1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af3bce5dfe303e66f3a8098a26e825ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af4b83974c53d0a3c5070b96a6679fb5 |
| publicationDate |
2021-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2021122687-A1 |
| titleOfInvention |
Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals |
| abstract |
Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals The inventors of the current invention have found a surprising positive effect of increased cAMP levels and / or manipulating the PTS system on the space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility of fine chemical production of a host organism. This was achieved by de-regulating adenylate cyclase cyaa by deleting the C-terminal regulatory region leading to increased cAMP levels or deleting the Crr protein activity (carbohydrate repression resistance) which regulates the carbohydate utilization system. Both lead to increased 2-fucosyllactoe and 6-sialyllactose production (human milk oligosaccharides) and increase carbohydrate usage. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023285585-A2 |
| priorityDate |
2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |