Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db502acd4e0b3cffdad9991da5b88d4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bd7a45a343acd10e3f5d8775dda2157 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16171 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 |
filingDate |
2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4dd086f0344b8c1b7f289246143aa85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59acd0269c120cc4d5c4dd03e95803f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a06b8ececc5c21508c943e1b4fc6cb3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea66d4e762920c42ae3a5d2e90cda4f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e2446051d0995e443838dbfdd98da8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b4619b3802d891029e20118eea3393e |
publicationDate |
2021-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021055679-A1 |
titleOfInvention |
Chimeric hemagglutinin protein and a vaccine composition comprising the same |
abstract |
Provided is a chimeric hemagglutinin (HA) protein including an HA1 subunit and an HA2 subunit, in which the HA1 subunit is composed of a first domain derived from a parental HA1 subunit of a first subtype influenza virus and a second domain derived from a parental HA1 subunit of a second subtype influenza virus. The chimeric HA protein has improved thermal stability and can be used in a vaccine composition for preventing influenza virus infection. Also provided is a method of inducing an immune response against an influenza virus in a subject in need thereof that includes administering the chimeric HA protein to the subject, thereby conferring protection against the influenza virus infection on the subject. |
priorityDate |
2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |