| abstract |
Antibodies that bind specifically to epitopes present in the stem region of influenza A hemagglutination trimer and neutralize group 1 and group 2 subtypes of influenza A virus and their antigen binding fragment. Nucleic acids encoding immortalized B cells and single plasma cells that produce such antibodies and antibody fragments and epitopes that bind to such antibodies and antibody fragments. Furthermore, the use of antibodies, antibody fragments and epitopes in screening methods and in the diagnosis, treatment and prevention of influenza A virus infection. |