Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc5256be365101d0394467d78ffce395 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-978 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-18 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M1-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
filingDate |
2020-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c2ae7b19cf44366ad02b8001ea2db81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1dacfe0630cdaaf3d434eafb07fbf4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63d9d4b33759a1c6baedff0d9d7c37ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b3da600ad9ad2dddfd12d81df803094 |
publicationDate |
2021-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2021054375-A1 |
titleOfInvention |
Method for quantifying citrulline, oxidoreductase for quantification, composition for quantification, kit for quantification, and method for evaluating activity of peptidylarginine deiminase |
abstract |
Provided are: a new quantification method for measuring citrulline, which is associated with various diseases and is an especially useful biomarker for early diagnosis of rheumatoid arthritis; an enzyme for quantification; a composition for quantification; and a kit for quantification. Also provided is a method for evaluating the activity of PAD using a method for measuring citrulline. A method for quantifying citrulline, the method including adding an oxidoreductase to a sample, is provided. The oxidoreductase is an oxidase, and the concentration of citrulline may be determined by quantifying the hydrogen peroxide produced by adding the oxidase. Alternatively, the hydrogen peroxide produced by adding the oxidase may be reacted with a reagent to determine the concentration of citrulline. |
priorityDate |
2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |