| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa815277e907c9bf61c727388076593c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2006-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1764b156748a1de1dbfa153f4896feef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd3426460329e0c8041de85bd127c529 |
| publicationDate |
2007-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2007222055-A |
| titleOfInvention |
Method for producing a chromosome region deletion strain |
| abstract |
A large chromosomal region of several tens to hundred kb such as a biosynthetic gene cluster of a toxic substance such as aflatoxin is efficiently deleted, and even if genetic engineering manipulation is applied, it is encoded in the region. To provide a transformed bacterium that cannot produce toxic substances. A method for producing a chromosome region-deficient strain using a bacterium belonging to Trichomonadaceae that does not have a sexual generation and has a higher homologous recombination frequency due to suppression of the Ku gene. Comprising transforming the homologous region at both ends of the chromosomal region to be deleted, and then deleting the chromosomal region using homologous recombination based on the homologous region, Manufacturing method. [Selection] FIG. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021054375-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020095864-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3985100-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11306320-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012504390-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018207928-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020122231-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021256503-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018088902-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019168062-A1 |
| priorityDate |
2006-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |