| abstract |
The present disclosure relates generally to the field of oncology. In particular, the invention discloses a method of treating a Sal-like protein 4 (SALL4) expressing cancer in a subject, the method comprising administering an inhibitor of mitochondrial oxidative phosphorylation (OXPHOS) for a sufficient time and under conditions to treat the subject of the SALL4 expressing cancer. Examples of the OXPHOS inhibitors include Oligomycin, Efrapeptin, Antimycin, Leucinostatin and PI-103. |