abstract |
The invention relates to the field of antimicrobial materials, in particular to implantable and other medical devices, exhibiting antimicrobial activity. Provided is a method for providing a substrate with an antimicrobial coating comprising providing a substrate that is coated with a polyamine-functionalized polymer, and contacting said polyamine-functionalized polymer with an aqueous salt solution comprising at least one salt having a polarizability α37 at least 4Å3 determined at 37ºC The salt solution may comprise one or more of NaI, KI, NaBr, KBr, NaClO4, KClO4, Na2SO4, K2SO4, Na3PO4, K3PO4, Mg(NO3)2, Ca(NO3)2, (NH4)2SO4, NH4NO3, MgSO4, CaSO4, and Al(NO3)3. |