| abstract |
The present invention provides an antimicrobial surface polymer coating capable of killing or deactivating bacterial spores which comprises: (1) hyperbranched polymers having (a) at least one heterocyclic N- halamine terminal group, or (b) at least one quaternary ammonium terminal group, or (c) a mixture comprising at least one each of quaternary ammonium and heterocyclic N-halamine terminal groups; or (2) polyamidoamine dendrimers having at least one heterocyclic N- halamine terminal group, or (3) linear PEI with hydantoin and quaternary ammonium groups at each repeat unit. The coating is preferred where small molecule germinants are encapsulated within it. The substrate that is coated can be sterilized prior to applying the coating, but it is not required to do so. |