abstract |
The present invention relates to an antibody having enhanced binding affinity for endothelin A receptor or an antigen binding fragment thereof. In addition, the present invention relates to an antibody showing enhanced productivity and an antigen binding fragment thereof. Compared with conventional antibodies, the antibody developed in the present invention has an exceptional enhancement in binding affinity for antigens and productivity and as such, can be advantageously used as a therapeutic and diagnostic antibody for endothelin receptor A-related diseases. |